Publications


2019

  • Hötte, K., Koch, M., Hof, L., Tuppi, M., Moreth, T., Verstegen, M. M. A., van der Laan, L. J. W., Stelzer, E. H. K., & Pampaloni, F. (2019). Ultra-thin fluorocarbon foils optimise multiscale imaging of three-dimensional native and optically cleared specimens. Sci Rep, 9, 17292.
  • Aloia, L., McKie, M. A., Vernaz, G., Cordero-Espinoza, L., Aleksieva, N., van den Ameele, J., Antonica, F., Font-Cunill, B., Raven, A., Aiese Cigliano, R., Belenguer, G., Mort, R. L., Brand, A. H., Zernicka-Goetz, M., Forbes, S. J., Miska, E. A., & Huch, M. (2019). Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration. Nat Cell Biol, 21, 1321–1333.
  • Azzarelli, R., Rulands, S., Nestorowa, S., Davies, J., Campinoti, S., Gillotin, S., Bonfanti, P., Göttgens, B., Huch, M., Simons, B., & Philpott, A. (2019). Neurogenin3 phosphorylation controls reprogramming efficiency of pancreatic ductal organoids into endocrine cells. Scientific Reports, online.
  • Lancaster, M. A., & Huch, M. (2019). Disease modelling in human organoids. Disease Models & Mechanisms, online.
  • Prior, N., Inacio, P., & Huch, M. (2019). Liver organoids: from basic research to therapeutic applications. Gut, online.
  • Prior, N., Hindley, C. J., Rost, F., Meléndez, E., Lau, W. W. Y., Göttgens, B., Rulands, S., Simons, B. D., & Huch, M. (2019). Lgr5+ stem/progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool. Development, online.
  • Hoette, K., Koch, M., Hof, L., Tuppi, M., Moreth, T., Stelzer, E. H. K., & Pampaloni, F. (2019). Ultra-thin fluorocarbon foils optimize multiscale imaging of three-dimensional native and optically cleared specimens. bioRxiv, 533844.
  • Dijk, B. V., & Sadr, N. (2019). Pancreas organoids for type I diabetes mellitus-Is it feasible as a cell therapy?. In “Advancing Manufacture of Cell and Gene Therapies VI”, Baksh, Rietze, & Wall, ECI Symposium Series, 60.

2018

  • Prior, N., Hindley, C. J., Rost, F., Esteban, E. M., Lau, W. W. Y., Göttgens, B., Rulands, S., Simons, B. D., & Huch, M. (2018). Lgr5+ stem/progenitor cells reside at the apex of the embryonic hepatoblast pool. bioRxiv, 485870.
  • Rulands, S., Lescroart, F., Chabab, S., Hindley, C. J., Prior, N., Sznurkowska, M. K., Huch, M., Philpott, A., Blanpain, C., & Simons, B. D. (2018). Universality of clone dynamics during tissue development. Nature physics, 14(5), 469.
  • Viganò, M., Budelli, S., Lavazza, C., Montemurro, T., Montelatici, E., De Cesare, S., Lazzari, L., Orlandi, A. R., Lunghi, G., & Giordano, R. (2018). Tips and Tricks for Validation of Quality Control Analytical Methods in Good Manufacturing Practice Mesenchymal Stromal Cell Production. Stem Cells International, 2018, 1-16.

2017

  • Viganò, M., Giordano, R., & Lazzari, L. (2017). Challenges of running a GMP facility for regenerative medicine in a public hospital. Regenerative Medicine, 12(7), 803-813.
  • Huch, M., Knoblich, J. A., Lutolf, M. P., & Martinez-Arias, A. (2017). The hope and the hype of organoid research. Development, 144(6), 938-941.
  • Pampaloni, F., Mayer, B., Kabat Vel-Job, K., Ansari, N., Hötte, K., Kögel, D., & Stelzer, E. H. K. (2017). A novel cellular spheroid-based autophagy screen applying live fluorescence microscopy identifies nonactin as a strong inducer of autophagosomal turnover. SLAS DISCOVERY: Advancing Life Sciences R&D, 22(5), 558-570.
  • Broutier, L., Mastrogiovanni, G., Verstegen, M. M. A., Francies, H. E., Gavarró, L. M., Bradshaw, C. R., Allen, G. E., Arnes-Benito, R., Sidorova, O., Gaspersz, M. P., Georgakopoulos, N., Koo, B.-K., Dietmann, S., Davies, S. E., Praseedom, R. K., Lieshout, R., IJzermans, J. N. M., Wigmore, S. J., Saeb-Parsy, K., Garnett, M. J., van der Laan, L. J. W., & Huch, M. (2017). Human primary liver cancer–derived organoid cultures for disease modeling and drug screening. Nature Medicine, 23, 1424–1435.
  • Smyrek, I., & Stelzer, E. H. K. (2017). Quantitative three-dimensional evaluation of immunofluorescence staining for large whole mount spheroids with light sheet microscopy. Biomedical Optics Express, 8(2), 484-499.